NFL Odds, Spreads, Lines, Picks, Indianapolis Colts, Gardner Minshew
NFL Betting, Odds, Spreads, Lines, Indianapolis Colts, Gardner Minshew, Getty Images

Week 6 NFL Betting Lines, Spreads, Odds

All odds via FanDuel Sportsbook

  • Baltimore Ravens @ Tennessee Titans: +5.5
  • San Francisco 49ers @ Cleveland Browns: +9.5
  • Washington Commanders @ Atlanta Falcons: -1.5
  • Carolina Panthers @ Miami Dolphins: -14.5
  • Minnesota Vikings @ Chicago Bears: +3
  • Indianapolis Colts @ Jacksonville Jaguars: -3.5
  • New Orleans Saints @ Houston Texans: +1.5
  • Seattle Seahawks @ Cincinnati Bengals: -3
  • New England Patriots @ Las Vegas Raiders: -2.5
  • Detroit Lions @ Tampa Bay Buccaneers: +3
  • Arizona Cardinals @ Los Angeles Rams: -7
  • Philadelphia Eagles @ New York Jets: +6.5
  • New York Giants @ Buffalo Bills: -15.5
  • Dallas Cowboys @ Los Angeles Chargers: +1.5

Indianapolis Colts @ Jacksonville Jaguars

The Jaguars come into this game after spending two weeks in London. It was a successful trip as Jacksonville went 2-0 with victories over the Buffalo Bills and Atlanta Falcons. Now, they head back home to square off against the division-rival Indianapolis Colts.

The Colts will be without rookie quarterback Anthony Richardson. He was placed on injured reserve this week after suffering a shoulder injury in their win against the Titans. Journeyman quarterback Gardner Minshew will take over as the starter for the Colts.

Minshew has played quite a bit this season for the Colts. Richardson has been oft-injured during his rookie season, so Minshew should be ready for the challenge.

In 2023, Minshew is completing 69% of his passes with two touchdowns, no interceptions, and a 95.1 passer rating. He is more than capable of being a starting quarterback in the NFL and should have a favorable matchup this week in Jacksonville. The Jaguars are allowing the fourth-most passing yards in the NFL this season at 262.4 yards per game.

I think this is a great spot for the Colts. After spending two weeks in London and then traveling back home, I expect the Jaguars to be a little fatigued. I think the Colts will be able to play with the Jaguars offense and keep this game close.

The play: Indianapolis Colts: +4.5

New England Patriots @ Las Vegas Raiders

The Patriots are going through their worst start to a season in a long time. Sitting at 1-4, it feels as if they are playing for their season this week. After being outscored 72-3 in the last two weeks, I think the Patriots will come ready to play in Vegas.

It is incredibly hard to make a case for New England in this game for a variety of reasons. Their offense has scored three points in the last two games and is averaging a league-worst 11 points per game this season.

However, I think New England will be able to move the ball this week. They are going against a Raiders defense that is struggling in almost every category. Las Vegas ranks 29th in red zone efficiency, 27th in first downs, 30th in sacks, 29th in passing yards allowed, and 32nd in turnovers. I think New England will be able to score some points and get their offense back on track.

Even with their 1-4 start, the Patriots defense is still one of the better units in the NFL. They are allowing the fourth-fewest yards per drive and the sixth-lowest third down conversion rate. Against a Raiders offense that is 29th in third down conversion rate, the Patriots defense has a chance to get off the field quickly.

I think this is a good matchup for the Patriots and believe they can win this game outright.

The play: New England Patriots: +2.5

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Brendan Vander Vliet is a writer who specializes in NFL gambling content. Everything from spreads, totals, props, etc. is covered. Email: bvander_vliet[at]
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